Methanol → 3-(hydroxymethyl)-7,8,9,10-tetrahydro-5H-dipyrido[1,2-a:3',2'-e]pyrazin-6(6aH)-one

HRID 1114085

Reaction equation

HRID 1114085 reaction equation
[Al+3:23].[CH3:28][OH:29].[CH3:36][CH2:37][O:38][C:39](=[O:40])[CH3:41].[H-:21].[H-:22].[H-:25].[H-:26].[H-:27].[Li+:24].[Na+:20].[O:1]=[C:2]1[CH:3]2[N:4]([c:5]3[c:6]([cH:8][c:9]([C:12](=[O:13])[O:14][CH3:15])[cH:10][n:11]3)[NH:7]1)[CH2:16][CH2:17][CH2:18][CH2:19]2.[O:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1.[OH2:35]>>[O:1]=[C:2]1[CH:3]2[N:4]([c:5]3[c:6]([cH:8][c:9]([CH2:12][OH:13])[cH:10][n:11]3)[NH:7]1)[CH2:16][CH2:17][CH2:18][CH2:19]2

Participants

10

Reactant 9

HCID 887MethanolHCID 923Sodium ionHCID 962WaterHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride5×HCID 58324466Methyl 6-oxo-6,6a,7,8,9,10-hexahydro-5H-dipyrido[1,2-a:3',2'-e]pyrazine-3-carboxylate

Product 1

HCID 583244753-(hydroxymethyl)-7,8,9,10-tetrahydro-5H-dipyrido[1,2-a:3',2'-e]pyrazin-6(6aH)-one

Sources & evidence

ORD record
ord-78f3968f5e8240d89e6428cddaec7c2b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Linked notes

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