Ammonium → 2-(3-Chloro-propyl)-3-methylbenzofuran

Reaction equation

[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[CH3:1][CH2:2][CH2:3][CH2:4][Li:5].[CH3:6][c:7]1[cH:8][o:9][c:10]2[c:11]1[cH:12][cH:13][cH:14][cH:15]2.[Cl-:21].[Cl:16][CH2:17][CH2:18][CH2:19][I:20].[Cu:28][I:29].[NH4+:22]>>[CH3:6][c:7]1[c:8]([CH2:19][CH2:18][CH2:17][Cl:16])[o:9][c:10]2[c:11]1[cH:12][cH:13][cH:14][cH:15]2

Participants

Reactant 7

HCID 223Ammonium

HCID 312Chloride

HCID 8028Tetrahydrofuran

HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

HCID 813631-Chloro-3-iodopropane

HCID 889393-Methylbenzofuran

HCID 178418339Butyllithium

Product 1

HCID 229895512-(3-Chloro-propyl)-3-methylbenzofuran

Sources & evidence

ORD record: ord-54cda6f70ff94dc880ef6b29624812bb
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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