Dimethylformamide → methyl 3-[(5-chloro-1H-pyrrolo[2,3-c]pyridine-2-carbonyl)amino]-2-hydroxy-4-phenylbutanoate

HRID 117211

Reaction equation

HRID 117211 reaction equation
[CH3:14][O:15][C:16]([CH:17]([CH:18]([CH2:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)[NH2:26])[OH:27])=[O:28].[CH3:48][CH2:49][N:50]=[C:51]=[N:52][CH2:53][CH2:54][CH2:55][N:56]([CH3:57])[CH3:58].[CH:39]([N:40]([CH2:41][CH3:42])[CH:43]([CH3:44])[CH3:45])([CH3:46])[CH3:47].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([cH:6][n:7]1)[nH:8][c:9]([C:11](=[O:12])[OH:13])[cH:10]2.[O:59]=[CH:60][N:61]([CH3:62])[CH3:63].[OH:29][n:30]1[c:31]2[c:32]([cH:33][cH:34][cH:35][cH:36]2)[n:37][n:38]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([cH:6][n:7]1)[nH:8][c:9]([C:11](=[O:13])[NH:26][CH:18]([CH:17]([C:16]([O:15][CH3:14])=[O:28])[OH:27])[CH2:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)[cH:10]2

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 757711-HydroxybenzotriazoleHCID 81531DiisopropylethylamineHCID 5239179Methyl 3-amino-2-hydroxy-4-phenylbutanoateHCID 446307045-chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid

Product 1

HCID 72767426methyl 3-[(5-chloro-1H-pyrrolo[2,3-c]pyridine-2-carbonyl)amino]-2-hydroxy-4-phenylbutanoate

Sources & evidence

ORD record
ord-52be6546baf3485d86dba9de13c8cb26
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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