Tetrahydrofuran → 2-(2,6-dichlorophenyl)-6,7-difluoro-3H-benzoimidazole-5-carboxylic acid quinolin-2-ylamide

HRID 120478

Reaction equation

HRID 120478 reaction equation
[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH:34]([N:35]([CH2:36][CH3:37])[CH:38]([CH3:39])[CH3:40])([CH3:41])[CH3:42].[Cl:1][c:2]1[c:3](-[c:9]2[nH:10][c:11]3[c:12]([n:13]2)[c:14]([F:22])[c:15]([F:21])[c:16]([C:18](=[O:19])[Cl:20])[cH:17]3)[c:4]([Cl:8])[cH:5][cH:6][cH:7]1.[n:23]1[c:24]([NH2:33])[cH:25][cH:26][c:27]2[cH:28][cH:29][cH:30][cH:31][c:32]12>>[Cl:1][c:2]1[c:3](-[c:9]2[nH:10][c:11]3[c:12]([n:13]2)[c:14]([F:22])[c:15]([F:21])[c:16]([C:18](=[O:19])[NH:33][c:24]2[n:23][c:32]4[c:27]([cH:26][cH:25]2)[cH:28][cH:29][cH:30][cH:31]4)[cH:17]3)[c:4]([Cl:8])[cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 113792-AminoquinolineHCID 81531DiisopropylethylamineHCID 866512642-(2,6-dichlorophenyl)-6,7-difluoro-3H-benzoimidazole-5-carbonyl chloride

Product 1

HCID 669652202-(2,6-dichlorophenyl)-6,7-difluoro-3H-benzoimidazole-5-carboxylic acid quinolin-2-ylamide

Sources & evidence

ORD record
ord-7daa80b50e6e49dd914bf9df804df048
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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