Hydrochloric Acid → 5-Methyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid

HRID 1208672

Reaction equation

[Cl:1][c:2]1[c:3]([CH3:11])[cH:4][cH:5][c:6]([C:8](=[O:9])[OH:10])[n:7]1.[ClH:29].[N:18]12[CH2:19][CH2:20][CH2:21][N:22]=[C:23]1[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]2.[OH:12][CH2:13][C:14]([F:15])([F:16])[F:17]>>[c:2]1([O:12][CH2:13][C:14]([F:15])([F:16])[F:17])[c:3]([CH3:11])[cH:4][cH:5][c:6]([C:8](=[O:9])[OH:10])[n:7]1

Participants

Reactant 4

HCID 313Hydrochloric Acid

HCID 64092,2,2-Trifluoroethanol

HCID 811841,8-Diazabicyclo(5.4.0)undec-7-ene

HCID 183244376-Chloro-5-methylpyridine-2-carboxylic acid

Product 1

HCID 710875095-Methyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid

Sources & evidence

ORD record: ord-a1f980cdc32347cd907882bfcdf19484
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Linked notes

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