Tetrahydrofuran → 2,2,2-Trifluoro-N-{2-(methyloxy)-5[(trimethylsilyl)ethynyl]phenyl}-acetamide
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([O:15][CH3:16])[c:6]([NH:8][C:9]([C:10]([F:11])([F:12])[F:13])=[O:14])[cH:7]1.[CH2:64]1[O:65][CH2:66][CH2:67][CH2:68]1.[CH3:17][Si:18]([CH3:19])([CH3:20])[C:21]#[CH:22].[Pd:23]([Cl:24])[Cl:25].[c:26]1([P:27]([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[cH:40][cH:41][cH:42][cH:43][cH:44]1.[c:45]1([P:46]([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[cH:59][cH:60][cH:61][cH:62][cH:63]1>>[c:2]1([C:22]#[C:21][Si:18]([CH3:17])([CH3:19])[CH3:20])[cH:3][cH:4][c:5]([O:15][CH3:16])[c:6]([NH:8][C:9]([C:10]([F:11])([F:12])[F:13])=[O:14])[cH:7]1
