Chloride → (2,4-Dichloro-pyrimidin-5-yl)-(2-methylsulfanyl-pyrimidin-4-yl)-methanol

Reaction equation

[Br:1][c:2]1[c:3]([Cl:9])[n:4][c:5]([Cl:8])[n:6][cH:7]1.[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH3:15][S:16][c:17]1[n:18][cH:19][cH:20][c:21]([CH:23]=[O:24])[n:22]1.[CH:11]([Mg+:12])([CH3:13])[CH3:14].[Cl-:10]>>[c:2]1([CH:23]([c:21]2[cH:20][cH:19][n:18][c:17]([S:16][CH3:15])[n:22]2)[OH:24])[c:3]([Cl:9])[n:4][c:5]([Cl:8])[n:6][cH:7]1

Participants

Reactant 5

HCID 312Chloride

HCID 8028Tetrahydrofuran

HCID 2899735-Bromo-2,4-dichloropyrimidine

HCID 154070082-Methylsulfanylpyrimidine-4-carbaldehyde

HCID 178461726HCID 178461726, compound

Product 1

HCID 86667954(2,4-Dichloro-pyrimidin-5-yl)-(2-methylsulfanyl-pyrimidin-4-yl)-methanol

Sources & evidence

ORD record: ord-1712ba054ade4a79b357dd37d87b6d5b
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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