Ammonium → Methyl 5-(difluoromethoxy)picolinate

HRID 124229

Reaction equation

HRID 124229 reaction equation
[C:1](=[O:2])([O-:3])[O-:4].[CH3:37][CH2:38][O:39][C:40](=[O:41])[CH3:42].[Cl-:30].[Cl:7][C:8]([C:9]([c:10]1[cH:11][cH:12][cH:13][cH:14][cH:15]1)=[O:16])([F:17])[F:18].[Cs+:5].[Cs+:6].[NH4+:31].[O:32]=[CH:33][N:34]([CH3:35])[CH3:36].[OH:19][c:20]1[cH:21][cH:22][c:23]([C:26](=[O:27])[O:28][CH3:29])[n:24][cH:25]1>>[CH:8]([F:17])([F:18])[O:19][c:20]1[cH:21][cH:22][c:23]([C:26](=[O:27])[O:28][CH3:29])[n:24][cH:25]1

Participants

9

Reactant 8

HCID 223AmmoniumHCID 312ChlorideHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 2382962-Chloro-2,2-difluoroacetophenoneHCID 4715126Methyl 5-hydroxypyridine-2-carboxylate

Product 1

HCID 57827732Methyl 5-(difluoromethoxy)picolinate

Sources & evidence

ORD record
ord-2d248ae3730d42c481c47d1ac13de09d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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