Tetrahydrofuran → 3-[4-(1-(isopropylsulfonylaminocarbonyl)-1-(3,4-methylenedioxyphenyl)methoxy)-3,5-dipropylphenyl-methyl]-5,7-dimethyl-2-ethyl-3H-imidazo[4,5-b]pyridine

HRID 124881

Reaction equation

HRID 124881 reaction equation
[C:1](=[O:2])([OH:3])[CH:4]([O:5][c:6]1[c:7]([CH2:29][CH2:30][CH3:31])[cH:8][c:9]([CH2:15][n:16]2[c:17]([CH2:27][CH3:28])[n:18][c:19]3[c:20]2[n:21][c:22]([CH3:26])[cH:23][c:24]3[CH3:25])[cH:10][c:11]1[CH2:12][CH2:13][CH3:14])[c:32]1[cH:33][c:34]2[c:35]([cH:36][cH:37]1)[O:38][CH2:39][O:40]2.[C:41]([n:42]1[cH:43][cH:44][n:45][cH:46]1)([n:47]1[cH:48][cH:49][n:50][cH:51]1)=[O:52].[CH2:71]1[O:72][CH2:73][CH2:74][CH2:75]1.[CH:53]([CH3:54])([CH3:55])[S:56](=[O:57])(=[O:58])[NH2:59].[N:60]12[CH2:61][CH2:62][CH2:63][N:64]=[C:65]1[CH2:66][CH2:67][CH2:68][CH2:69][CH2:70]2>>[C:1](=[O:3])([CH:4]([O:5][c:6]1[c:7]([CH2:29][CH2:30][CH3:31])[cH:8][c:9]([CH2:15][n:16]2[c:17]([CH2:27][CH3:28])[n:18][c:19]3[c:20]2[n:21][c:22]([CH3:26])[cH:23][c:24]3[CH3:25])[cH:10][c:11]1[CH2:12][CH2:13][CH3:14])[c:32]1[cH:33][c:34]2[c:35]([cH:36][cH:37]1)[O:38][CH2:39][O:40]2)[NH:59][S:56]([CH:53]([CH3:54])[CH3:55])(=[O:57])=[O:58]

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 682631,1'-CarbonyldiimidazoleHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 3549191Propane-2-sulfonamideHCID 19010493Benzo[1,3]dioxol-5-yl-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetic acid

Product 1

HCID 190104903-[4-(1-(isopropylsulfonylaminocarbonyl)-1-(3,4-methylenedioxyphenyl)methoxy)-3,5-dipropylphenyl-methyl]-5,7-dimethyl-2-ethyl-3H-imidazo[4,5-b]pyridine

Sources & evidence

ORD record
ord-d80f085e55a646a194f45bb6bad74f9a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

Loading…