4-Iodoaniline → 1-[4-(4-Amino-phenyl)-but-3-ynyl]-4-benzyl-piperidin-4-ol
Reaction equation
[CH2:1]([C:8]1([OH:18])[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][C:16]#[CH:17])[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.I[C:20]1[CH:26]=[CH:25][C:23]([NH2:24])=[CH:22][CH:21]=1>CCN(CC)CC.[Cu]I.Cl[Pd](Cl)([P](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)[P](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1>[NH2:24][C:23]1[CH:25]=[CH:26][C:20]([C:17]#[C:16][CH2:15][CH2:14][N:11]2[CH2:12][CH2:13][C:8]([CH2:1][C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)([OH:18])[CH2:9][CH2:10]2)=[CH:21][CH:22]=1Participants
6
