4-Bromophenol → p-Bromo-(1-methoxyethoxy)benzene

HRID 129365

Reaction equation

HRID 129365 reaction equation
[CH:1]1[C:6]([OH:7])=[CH:5][CH:4]=[C:3]([Br:8])[CH:2]=1.[CH:9]([O:11][CH3:12])=[CH2:10]>>[Br:8][C:3]1[CH:4]=[CH:5][C:6]([O:7][CH:9]([O:11][CH3:12])[CH3:10])=[CH:1][CH:2]=1

Participants

3

Reactant 2

HCID 78084-BromophenolHCID 7861Methyl vinyl ether

Product 1

HCID 22908633p-Bromo-(1-methoxyethoxy)benzeneYield 90%

Procedure

Using p-bromophenol (17.3 g, 0.1 mole) and methyl vinyl ether (14.0 g, 0.2 mole), the reaction was carried out in the same manner as described in Synthesis Example 1, (1), and the crude oil (24 g) was purified by distillation under reduced pressure to afford 20.8 g of p-bromo-(1-methoxyethoxy)benzene as a pale yellow oil having a boiling point 89-90° C./2 mmHg.

Workup

  1. customas described in Synthesis Example 1, (1),
  2. distillationthe crude oil (24 g) was purified by distillation under reduced pressure

Sources & evidence

ORD record
ord-24808c6fb6474ee0bab5996c316c4c25
Source dataset
uspto-grants-1995_11
Patent number
US05468589

Linked notes

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