Acetate → Benzyl 3-(6-amino-3-pyridinyl)prop-2-enoate

HRID 137382

Reaction equation

HRID 137382 reaction equation
[C:52](#[N:53])[CH2:54][CH3:55].[C:9]([CH:10]=[CH2:11])(=[O:12])[O:13][CH2:14][c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1.[CH:43]([N:44]([CH:45]([CH3:46])[CH3:47])[CH2:48][CH3:49])([CH3:50])[CH3:51].[NH2:1][c:2]1[n:3][cH:4][c:5]([Br:8])[cH:6][cH:7]1.[O-:57][C:58]([CH3:59])=[O:60].[O-:61][C:62]([CH3:63])=[O:64].[Pd+2:56].[c:21]1([CH3:22])[cH:23][cH:24][cH:25][cH:26][c:27]1[P:28]([c:29]1[cH:30][cH:31][cH:32][cH:33][c:34]1[CH3:35])[c:36]1[cH:37][cH:38][cH:39][cH:40][c:41]1[CH3:42]>>[NH2:1][c:2]1[n:3][cH:4][c:5]([CH:11]=[CH:10][C:9](=[O:12])[O:13][CH2:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 7854PropionitrileHCID 706222-Amino-5-bromopyridineHCID 75617Benzyl acrylateHCID 80271Tri-o-tolylphosphineHCID 81531DiisopropylethylamineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

Product 1

HCID 70794459Benzyl 3-(6-amino-3-pyridinyl)prop-2-enoate

Sources & evidence

ORD record
ord-6951996d89864696bcb974380ee767bf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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