Creatine → Creatine

HRID 1419203Notes

Reaction equation

HRID 1419203 reaction equation
O.C(O)(=O)C(C)=O.[O:8]=[C:9]([CH2:11][N:12]([C:14](=[NH:16])[NH2:15])[CH3:13])[OH:10].[O:17]=[C:18]([CH2:20][N:21]([C:23](=[NH:25])[NH2:24])[CH3:22])O.C([O-])(=O)C(C)=O.O.O=C(CN(C(=N)N)C)O>O>[O:8]=[C:9]([CH2:11][N:12]([C:14](=[NH:15])[NH2:16])[CH3:13])[OH:10].[CH3:22][N:21]1[C:23]([NH2:25])=[N:24][C:18](=[O:17])[CH2:20]1

Participants

7

Reactant 4

HCID 586CreatineHCID 80116Creatine MonohydrateHCID 107735PyruvateHCID 9881182Creatine pyruvate monohydrate

Product 2

HCID 586CreatineHCID 588creatinine

Reagents, catalysts & solvents 1

HCID 962WaterSolvent3×

Procedure

Creatine pyruvate monohydrate may be represented by the empirical formula: C3H3O3-.C4H10O2N3+.H2O. The actual structural formula is now known for a certainty. However, it is known that the reaction between creatine and pyruvate is exothermic and that an organic salt is formed. It is also known that the salt formed is of relatively pure quality in that the product formed is a crystalline solid that has a definite decomposition point of 112°-114° C. Such a product is significantly different from its reactants. Creatine monohydrate is a solid that is sparingly soluble in water and that equilibrates in water to form creatine and creatinine. Pyruvic acid is a liquid that polymerizes and decomposes on standing unless stored in an airtight container.

Workup

  1. customis formed
  2. customformed
  3. customformed

Sources & evidence

ORD record
ord-4005a4b141f74f238fc0eef647600090
Source dataset
uspto-grants-1999_03
Patent number
US05886040

Reaction notes

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