1,2-Dichloroethane → 1-(6-methoxyspiro[3,4-dihydro-2H-isoquinoline-1,4'-piperidine]-1'-yl)-3-[2-(trifluoromethyl)phenyl]prop-2-en-1-one
Reaction equation
[CH2:43]([Cl:44])[CH2:45][Cl:46].[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:10]([cH:11][cH:12]1)[C:9]1([NH:8][CH2:7][CH2:6]2)[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]1.[CH3:51][CH2:52][O:53][C:54]([CH3:55])=[O:56].[Cl:48][CH2:49][Cl:50].[ClH:47].[F:18][C:19]([c:20]1[c:21]([CH:22]=[CH:23][C:24](=[O:25])[OH:26])[cH:27][cH:28][cH:29][cH:30]1)([F:31])[F:32].[OH:33][n:34]1[c:35]2[c:36]([cH:37][cH:38][cH:39][cH:40]2)[n:41][n:42]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:10]([cH:11][cH:12]1)[C:9]1([NH:8][CH2:7][CH2:6]2)[CH2:13][CH2:14][N:15]([C:24]([CH:23]=[CH:22][c:21]2[c:20]([C:19]([F:18])([F:31])[F:32])[cH:30][cH:29][cH:28][cH:27]2)=[O:25])[CH2:16][CH2:17]1
