Hydrochloric Acid → 2-(4-(Trifluoromethyl)piperidin-1-ylsulfonyl)benzonitrile

HRID 144347

Reaction equation

HRID 144347 reaction equation
[C:1](#[N:2])[c:3]1[c:4]([S:9](=[O:10])(=[O:11])[Cl:12])[cH:5][cH:6][cH:7][cH:8]1.[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:13][CH2:14][N:15]([CH2:16][CH3:17])[CH2:18][CH3:19].[ClH:20].[F:21][C:22]([CH:23]1[CH2:24][CH2:25][NH:26][CH2:27][CH2:28]1)([F:29])[F:30]>>[C:1](#[N:2])[c:3]1[c:4]([S:9](=[O:10])(=[O:11])[N:26]2[CH2:25][CH2:24][CH:23]([C:22]([F:21])([F:29])[F:30])[CH2:28][CH2:27]2)[cH:5][cH:6][cH:7][cH:8]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 1364694-(Trifluoromethyl)piperidineHCID 5223472-Cyanobenzenesulfonyl Chloride

Product 1

HCID 655362792-(4-(Trifluoromethyl)piperidin-1-ylsulfonyl)benzonitrile

Sources & evidence

ORD record
ord-6255514842e44cbfbcb6dfeb82cc4564
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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