Sodium ion → 5-Bromo-2-chloro-4-(2-ethoxyphenoxy)pyrimidine

HRID 150415

Reaction equation

HRID 150415 reaction equation
[Br:13][c:14]1[c:15]([Cl:21])[n:16][c:17]([Cl:20])[n:18][cH:19]1.[CH3:22][CH2:23][O:24][C:25]([CH3:26])=[O:27].[CH3:33][C:34]#[N:35].[H-:2].[Na+:1].[O:28]=[CH:29][N:30]([CH3:31])[CH3:32].[O:3]([CH2:4][CH3:5])[c:6]1[c:7]([OH:12])[cH:8][cH:9][cH:10][cH:11]1>>[O:3]([CH2:4][CH3:5])[c:6]1[c:7]([O:12][c:15]2[c:14]([Br:13])[cH:19][n:18][c:17]([Cl:20])[n:16]2)[cH:8][cH:9][cH:10][cH:11]1

Participants

8

Reactant 7

HCID 923Sodium ionHCID 6228DimethylformamideHCID 6342AcetonitrileHCID 8857Ethyl AcetateHCID 667552-EthoxyphenolHCID 166653HydrideHCID 2899735-Bromo-2,4-dichloropyrimidine

Product 1

HCID 790765415-Bromo-2-chloro-4-(2-ethoxyphenoxy)pyrimidine

Sources & evidence

ORD record
ord-2b4f8fefe12b45829a57a2dbcf3e706e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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