4-(Dimethylamino)pyridine → 2-(3,5-bis-trifluoromethyl-phenyl)-N-methyl-N-[2-methyl-6'-(4-methyl-piperazin-1-yl)-[3,4']bipyridinyl-3'-yl]-isobutyramide
Reaction equation
[CH3:1][N:2]1[CH2:3][CH2:4][NH:5][CH2:6][CH2:7]1.[CH3:43][N:44]([c:45]1[cH:46][cH:47][n:48][cH:49][cH:50]1)[CH3:51].[CH3:52][O:53][C:54]([CH3:55])([CH3:56])[CH3:57].[F:8][C:9]([c:10]1[cH:11][c:12]([C:20]([C:21](=[O:22])[N:23]([CH3:24])[c:25]2[cH:26][n:27][c:28]([Cl:38])[cH:29][c:30]2-[c:31]2[c:32]([CH3:37])[n:33][cH:34][cH:35][cH:36]2)([CH3:39])[CH3:40])[cH:13][c:14]([C:16]([F:17])([F:18])[F:19])[cH:15]1)([F:41])[F:42]>>[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([c:28]2[n:27][cH:26][c:25]([N:23]([C:21]([C:20]([c:12]3[cH:11][c:10]([C:9]([F:8])([F:41])[F:42])[cH:15][c:14]([C:16]([F:17])([F:18])[F:19])[cH:13]3)([CH3:39])[CH3:40])=[O:22])[CH3:24])[c:30](-[c:31]3[c:32]([CH3:37])[n:33][cH:34][cH:35][cH:36]3)[cH:29]2)[CH2:6][CH2:7]1Participants
5
