Ammonium → Tert-butyl 4-[4-iodo-1-(2-pyrrolidin-1-ylethyl)imidazol-2-yl]piperidine-1-carboxylate

HRID 1548847

Reaction equation

HRID 1548847 reaction equation
[CH3:28][CH:29]1[CH2:30][CH2:31][CH2:32][O:33]1.[CH:35]([Mg+:36])([CH3:37])[CH3:38].[Cl-:34].[Cl-:44].[I:1][c:2]1[n:3][c:4]([CH:15]2[CH2:16][CH2:17][N:18]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:19][CH2:20]2)[n:5]([CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][CH2:13][CH2:14]2)[c:6]1[I:7].[NH4+:45].[O:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1>>[I:1][c:2]1[n:3][c:4]([CH:15]2[CH2:16][CH2:17][N:18]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:19][CH2:20]2)[n:5]([CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][CH2:13][CH2:14]2)[cH:6]1

Participants

7

Reactant 6

HCID 223AmmoniumHCID 312Chloride2×HCID 73012-MethyltetrahydrofuranHCID 8028TetrahydrofuranHCID 67112102Tert-butyl 4-[4,5-diiodo-1-(2-pyrrolidin-1-ylethyl)imidazol-2-yl]piperidine-1-carboxylateHCID 178461726HCID 178461726, compound

Product 1

HCID 67112018Tert-butyl 4-[4-iodo-1-(2-pyrrolidin-1-ylethyl)imidazol-2-yl]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-719cb0357b6e435bbdf513850884e253
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Linked notes

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