Water → N-[3-({2-[(cyclopropylcarbonyl)amino][1,2,4]triazolo[1,5-a]pyridin-6-yl}oxy)phenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide

HRID 1558474

Reaction equation

HRID 1558474 reaction equation
[CH3:28][CH2:29][N:30]([CH2:31][CH3:32])[CH2:33][CH3:34].[CH:35]1([C:38](=[O:39])[Cl:40])[CH2:36][CH2:37]1.[NH2:1][c:2]1[n:3][n:4]2[c:5]([cH:6][cH:7][c:8]([O:10][c:11]3[cH:12][c:13]([NH:17][C:18](=[O:19])[c:20]4[cH:21][c:22]([CH3:26])[n:23][n:24]4[CH3:25])[cH:14][cH:15][cH:16]3)[cH:9]2)[n:27]1.[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1.[OH2:46]>>[NH:1]([c:2]1[n:3][n:4]2[c:5]([cH:6][cH:7][c:8]([O:10][c:11]3[cH:12][c:13]([NH:17][C:18](=[O:19])[c:20]4[cH:21][c:22]([CH3:26])[n:23][n:24]4[CH3:25])[cH:14][cH:15][cH:16]3)[cH:9]2)[n:27]1)[C:38]([CH:35]1[CH2:36][CH2:37]1)=[O:39]

Participants

6

Reactant 5

HCID 962WaterHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 77637Cyclopropanecarbonyl chlorideHCID 57749195N-{3-[(2-amino[1,2,4]triazolo[1,5-a]pyridin-6-yl)oxy]phenyl}-1,3-dimethyl-1H-pyrazole-5-carboxamide

Product 1

HCID 25127856N-[3-({2-[(cyclopropylcarbonyl)amino][1,2,4]triazolo[1,5-a]pyridin-6-yl}oxy)phenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide

Sources & evidence

ORD record
ord-d26358a669df412fb3ac7403a6054ba6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Linked notes

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