Hydrochloric Acid → 1-Benzyl-4-cyano-4-phenylpiperidine

HRID 156453

Reaction equation

HRID 156453 reaction equation
[Br:16][CH2:17][c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1.[C:24](=[O:25])([O-:26])[O-:27].[ClH:1].[K+:28].[K+:29].[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1.[OH2:30].[c:2]1([C:8]2([C:14]#[N:15])[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2)[cH:3][cH:4][cH:5][cH:6][cH:7]1>>[c:2]1([C:8]2([C:14]#[N:15])[CH2:9][CH2:10][N:11]([CH2:17][c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)[CH2:12][CH2:13]2)[cH:3][cH:4][cH:5][cH:6][cH:7]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 962WaterHCID 7498Benzyl BromideHCID 8028TetrahydrofuranHCID 19660Carbonate IonHCID 1811384-Piperidinecarbonitrile, 4-phenyl-

Product 1

HCID 1914081-Benzyl-4-cyano-4-phenylpiperidine

Sources & evidence

ORD record
ord-7d885b4c64fe44ec9ce722f25c999f19
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

Loading…