Hydrochloric Acid → N-adamantan-2-yl-2,3-dihydro-4H-1,4-benzoxazine-4-carboxamide

HRID 172170

Reaction equation

HRID 172170 reaction equation
[CH3:13][CH2:14][N:15]([CH2:16][CH3:17])[CH2:18][CH3:19].[CH:31]12[CH:32]([NH2:41])[CH:33]3[CH2:34][CH:35]([CH2:36][CH:37]([CH2:38]1)[CH2:39]3)[CH2:40]2.[CH:42]([Cl:43])([Cl:44])[Cl:45].[Cl:1][C:2]([Cl:3])([O:4][C:5]([O:6][C:7]([Cl:8])([Cl:9])[Cl:10])=[O:11])[Cl:12].[ClH:30].[O:20]1[CH2:21][CH2:22][NH:23][c:24]2[c:25]1[cH:26][cH:27][cH:28][cH:29]2.[OH2:46]>>[C:5](=[O:11])([N:23]1[CH2:22][CH2:21][O:20][c:25]2[c:24]1[cH:29][cH:28][cH:27][cH:26]2)[NH:41][CH:32]1[CH:31]2[CH2:38][CH:37]3[CH2:36][CH:35]([CH2:34][CH:33]1[CH2:39]3)[CH2:40]2

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 962WaterHCID 6212ChloroformHCID 8471TriethylamineHCID 253322-AminoadamantaneHCID 94429TriphosgeneHCID 5850963,4-Dihydro-2H-1,4-benzoxazine

Product 1

HCID 25134157N-adamantan-2-yl-2,3-dihydro-4H-1,4-benzoxazine-4-carboxamide

Sources & evidence

ORD record
ord-650e71bff46e43e9b3ddae931af669f0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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