4-Methoxybenzaldehyde → S-ethyl (E)-3-(4-methoxyphenyl)prop-2-enethioate
Reaction equation
COc1ccc(C=O)cc1.CCSC(=O)CC(=O)O>C1CCNC1.CN(C)c1ccncc1.Cc1ccccc1>CCSC(=O)/C=C/c1ccc(OC)cc1Participants
6
Conditions
- Temperature
- 50 °C
Workup
- temperatureThe product mixture was cooled to 25 °C.
- filtrationFiltered through a pad of celite · Keep Organic
- wash"The celite was washed with ethyl acetate (3 x 1 mL)."
- concentrationThe filtrate was concentrated under reduced pressure
- additionA 0.07 M stock solution of the internal standard ethylene carbonate (0.70 mL in CDCl3) was added.
Sources & evidence
- ORD record
- ord-ea7532b6e99d4563a58ec8c332f2b300
- Source dataset
- Bayesian optimization of 5 decarboxylative olefination reactions
Reaction notes
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