Tetrahydrofuran → 2-bromo-3-cyclohexyl-N-(dimethylsulfamoyl)-1H-indole-6-carboxamide

HRID 184587

Reaction equation

HRID 184587 reaction equation
[Br:13][c:14]1[nH:15][c:16]2[cH:17][c:18]([C:29](=[O:30])[OH:31])[cH:19][cH:20][c:21]2[c:22]1[CH:23]1[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]1.[C:1]([c:2]1[nH:3][cH:4][cH:5][n:6]1)([c:7]1[nH:8][cH:9][cH:10][n:11]1)=[O:12].[CH2:39]1[CH2:40][CH2:41][C:42]2=[N:47][CH2:46][CH2:45][CH2:44][N:43]2[CH2:48][CH2:49]1.[CH2:50]1[O:51][CH2:52][CH2:53][CH2:54]1.[CH3:32][N:33]([S:34](=[O:35])(=[O:36])[NH2:37])[CH3:38].[CH3:55][CH2:56][O:57][C:58]([CH3:59])=[O:60]>>[Br:13][c:14]1[nH:15][c:16]2[cH:17][c:18]([C:29](=[O:31])[NH:37][S:34]([N:33]([CH3:32])[CH3:38])(=[O:35])=[O:36])[cH:19][cH:20][c:21]2[c:22]1[CH:23]1[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]1

Participants

7

Reactant 6

HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 134472N,N-DimethylsulfamideHCID 5142612-bromo-3-cyclohexyl-1H-indole-6-carboxylic acidHCID 5250894Bis-(1H-imidazol-2-YL)-methanone

Product 1

HCID 587651502-bromo-3-cyclohexyl-N-(dimethylsulfamoyl)-1H-indole-6-carboxamide

Sources & evidence

ORD record
ord-d58d49277f0b490f9dccf7db8c540dc5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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