Chloride → 3-chloro-N-[2-hydroxy-5-(trifluoromethyl)pyridin-3-yl]isonicotinamide
Reaction equation
[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[Cl-:1].[Cl:2][c:3]1[c:4]([C:5](=[O:6])[OH:7])[cH:8][cH:9][n:10][cH:11]1.[NH2:17][c:18]1[c:19]([OH:28])[n:20][cH:21][c:22]([C:24]([F:25])([F:26])[F:27])[cH:23]1.[O:12]=[CH:13][N:14]([CH3:15])[CH3:16].[OH2:36]>>[Cl:2][c:3]1[c:4]([C:5](=[O:7])[NH:17][c:18]2[c:19]([OH:28])[n:20][cH:21][c:22]([C:24]([F:25])([F:26])[F:27])[cH:23]2)[cH:8][cH:9][n:10][cH:11]1Participants
7
Sources & evidence
- ORD record
- ord-87f292884fea4581af9dc919dec402f7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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