Hydrochloric Acid → N-(2-fluoro-5-{[2-(isobutyrylamino)imidazo[1,2-b]pyridazin-6-yl]oxy}phenyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide

HRID 186493

Reaction equation

HRID 186493 reaction equation
[CH3:30][CH:31]([C:32](=[O:33])[Cl:34])[CH3:35].[CH3:36][N:37]([CH3:38])[C:39](=[O:40])[CH3:41].[ClH:1].[NH2:2][c:3]1[n:4][c:5]2[n:6]([n:7][c:8]([O:11][c:12]3[cH:13][cH:14][c:15]([F:28])[c:16]([NH:18][C:19](=[O:20])[c:21]4[cH:22][c:23]([CH3:27])[n:24][n:25]4[CH3:26])[cH:17]3)[cH:9][cH:10]2)[cH:29]1>>[NH:2]([c:3]1[n:4][c:5]2[n:6]([n:7][c:8]([O:11][c:12]3[cH:13][cH:14][c:15]([F:28])[c:16]([NH:18][C:19](=[O:20])[c:21]4[cH:22][c:23]([CH3:27])[n:24][n:25]4[CH3:26])[cH:17]3)[cH:9][cH:10]2)[cH:29]1)[C:32]([CH:31]([CH3:30])[CH3:35])=[O:33]

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 31374DimethylacetamideHCID 62325Isobutyryl chlorideHCID 57505568N-[5-(2-aminoimidazo[1,2-b]pyridazin-6-yl)oxy-2-fluorophenyl]-2,5-dimethylpyrazole-3-carboxamide

Product 1

HCID 57505566N-(2-fluoro-5-{[2-(isobutyrylamino)imidazo[1,2-b]pyridazin-6-yl]oxy}phenyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide

Sources & evidence

ORD record
ord-8eba48130d2e44f493cb537f7767b404
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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