Hydrochloric Acid → 4-Penten-2-ol, 1,1,1-trifluoro-2-(trifluoromethyl)-

One mol of hexafluoroacetone was added dropwise at 0° C. to 1.1 mol of allylbromide in THF solution. The reaction was carried out at room temperature for 4 hours. After treating with HCl, the reaction mixture was extracted with H2O and ether, and the organic layer was evaporated under reduced pressure to provide an intermediate product, allylhexafluoroisopropanol. Cyclopentadiene (1 mol) and 1 mol of the intermediate product then were placed into a reactor and reacted at about 80° C. for about 24 hours.

1. extractionthe reaction mixture was extracted with H2O and ether
2. customthe organic layer was evaporated under reduced pressure

ORD record

ord-76561a4c03834dd59c082c51908e0bfa

Source dataset

uspto-grants-2004_07

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US06762268B2