Hydrochloric Acid → 2-(3-Piperidin-1-ylpyrrolidin-1-yl)-1,3-benzothiazol-6-amine

HRID 188642

Reaction equation

HRID 188642 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][c:7]([N:9]3[CH2:10][CH:11]([N:14]4[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]4)[CH2:12][CH2:13]3)[s:8]2)[cH:20][cH:21]1.[C:22]([P:23]([C:24]([CH3:25])([CH3:26])[CH3:27])[C:28]([CH3:29])([CH3:30])[CH3:31])([CH3:32])([CH3:33])[CH3:34].[CH3:35][Si:36]([N-:39][Si:37]([CH3:38])([CH3:40])[CH3:41])([CH3:42])[CH3:43].[CH3:48][c:49]1[cH:50][cH:51][cH:52][cH:53][cH:54]1.[ClH:45].[Li+:44].[Na+:47].[OH-:46]>>[c:2]1([NH2:39])[cH:3][c:4]2[c:5]([n:6][c:7]([N:9]3[CH2:10][CH:11]([N:14]4[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]4)[CH2:12][CH2:13]3)[s:8]2)[cH:20][cH:21]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 961HydroxideHCID 1140TolueneHCID 28486Lithium ionHCID 83681Tris(1,1-dimethylethyl)phosphineHCID 3280088Npc316347HCID 669061216-Bromo-2-(3-piperidin-1-ylpyrrolidin-1-yl)-1,3-benzothiazole

Product 1

HCID 632309052-(3-Piperidin-1-ylpyrrolidin-1-yl)-1,3-benzothiazol-6-amine

Sources & evidence

ORD record
ord-1e0f6ffd057047258c3ffc543c38a37f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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