Hydrogen Bromide → Benzyl 7-hydroxy-3,4-dihydroisoquinoline-2(1H)-carboxylate

HRID 194458

Reaction equation

HRID 194458 reaction equation
[BrH:1].[C:18]([O:19][CH2:20][c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1)(=[O:27])[Cl:28].[Na+:30].[O:13]1[CH2:14][CH2:15][CH2:16][CH2:17]1.[OH-:29].[OH:2][c:3]1[cH:4][cH:5][c:6]2[c:11]([cH:12]1)[CH2:10][NH:9][CH2:8][CH2:7]2>>[OH:2][c:3]1[cH:4][cH:5][c:6]2[c:11]([cH:12]1)[CH2:10][N:9]([C:18]([O:19][CH2:20][c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1)=[O:27])[CH2:8][CH2:7]2

Participants

7

Reactant 6

HCID 260Hydrogen BromideHCID 923Sodium ionHCID 961HydroxideHCID 8028TetrahydrofuranHCID 10387Benzyl chloroformateHCID 4192681,2,3,4-Tetrahydroisoquinolin-7-ol

Product 1

HCID 11254587Benzyl 7-hydroxy-3,4-dihydroisoquinoline-2(1H)-carboxylate

Sources & evidence

ORD record
ord-4b15ca5af4964e6ab01144898a071f04
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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