4-Methylmorpholine → tert-Butyl (2-{4-[({2-[(2,3-difluorobenzyl)thio]-6-methoxypyrimidin-4-yl}amino)sulfonyl]piperazin-1-yl}-2-oxoethyl)carbamate

Reaction equation

[C:1]([O:5][C:6]([NH:8][CH2:9][C:10]([OH:12])=O)=[O:7])([CH3:4])([CH3:3])[CH3:2].O.ON1C2C=CC=CC=2N=N1.Cl.[F:25][C:26]1[C:31]([F:32])=[CH:30][CH:29]=[CH:28][C:27]=1[CH2:33][S:34][C:35]1[N:40]=[C:39]([NH:41][S:42]([N:45]2[CH2:50][CH2:49][NH:48][CH2:47][CH2:46]2)(=[O:44])=[O:43])[CH:38]=[C:37]([O:51][CH3:52])[N:36]=1.CN1CCOCC1>CN(C=O)C>[F:25][C:26]1[C:31]([F:32])=[CH:30][CH:29]=[CH:28][C:27]=1[CH2:33][S:34][C:35]1[N:40]=[C:39]([NH:41][S:42]([N:45]2[CH2:46][CH2:47][N:48]([C:10](=[O:12])[CH2:9][NH:8][C:6](=[O:7])[O:5][C:1]([CH3:2])([CH3:3])[CH3:4])[CH2:49][CH2:50]2)(=[O:43])=[O:44])[CH:38]=[C:37]([O:51][CH3:52])[N:36]=1