4-Methylmorpholine → 4-{2-[2-(Benzyloxycarbonyl-methyl-amino)-propionylamino]-3,3-dimethyl-butyryl}-3-(3,4-difluoro-phenoxy)-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid tert-butyl ester

Reaction equation

[C:1]([N:11]([CH3:17])[C@H:12]([C:14]([OH:16])=O)[CH3:13])([O:3][CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:2].CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.CN1CCOCC1.[C:49]([O:53][C:54]([N:56]1[CH2:60][CH:59]([O:61][C:62]2[CH:67]=[CH:66][C:65]([F:68])=[C:64]([F:69])[CH:63]=2)[CH:58]2[N:70]([C:73](=[O:80])[CH:74]([NH2:79])[C:75]([CH3:78])([CH3:77])[CH3:76])[CH2:71][CH2:72][CH:57]12)=[O:55])([CH3:52])([CH3:51])[CH3:50]>CN1C(=O)CCC1.CCOC(C)=O.CCOCC>[C:49]([O:53][C:54]([N:56]1[CH2:60][CH:59]([O:61][C:62]2[CH:67]=[CH:66][C:65]([F:68])=[C:64]([F:69])[CH:63]=2)[CH:58]2[N:70]([C:73](=[O:80])[CH:74]([NH:79][C:14](=[O:16])[CH:12]([N:11]([C:1]([O:3][CH2:4][C:5]3[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=3)=[O:2])[CH3:17])[CH3:13])[C:75]([CH3:78])([CH3:77])[CH3:76])[CH2:71][CH2:72][CH:57]12)=[O:55])([CH3:52])([CH3:50])[CH3:51]