Tetrahydrofuran → 1-{2,6-Dimethyl-3-[3-methyl-5-(6-methyl-pyridin-2-yl)-thiophen-2-yl]-imidazo[1,2-b]pyridazin-8-yl}-propan-1-one
Reaction equation
[CH2:25]1[CH2:26][CH2:27][CH2:28][O:29]1.[CH3:1][c:2]1[n:3][c:4]2[n:5]([n:6][c:7]([CH3:10])[cH:8][cH:9]2)[c:11]1-[c:12]1[s:13][c:14](-[c:18]2[n:19][c:20]([CH3:24])[cH:21][cH:22][cH:23]2)[cH:15][c:16]1[CH3:17].[CH3:31][CH:32]([N-:33][CH:34]([CH3:35])[CH3:36])[CH3:37].[CH3:38][O:39][N:40]([CH3:41])[C:42](=[O:43])[CH2:44][CH3:45].[CH3:46][CH2:47][O:48][C:49]([CH3:50])=[O:51].[Li+:30]>>[CH3:1][c:2]1[n:3][c:4]2[n:5]([n:6][c:7]([CH3:10])[cH:8][c:9]2[C:28]([CH2:27][CH3:26])=[O:29])[c:11]1-[c:12]1[s:13][c:14](-[c:18]2[n:19][c:20]([CH3:24])[cH:21][cH:22][cH:23]2)[cH:15][c:16]1[CH3:17]
