Dimethylformamide → 1-methyl-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-indole-2-carboxamide

HRID 199080

Reaction equation

HRID 199080 reaction equation
[CH3:20][C:21]1([CH3:35])[O:22][B:23]([c:28]2[cH:29][cH:30][c:31]([NH2:32])[cH:33][cH:34]2)[O:24][C:25]1([CH3:26])[CH3:27].[CH3:48][N:49]([CH3:50])[CH:51]=[O:52].[CH3:7][n:8]1[c:9]([C:17](=[O:18])[OH:19])[cH:10][c:11]2[cH:12][cH:13][cH:14][cH:15][c:16]12.[CH:36]([N:37]([CH:38]([CH3:39])[CH3:40])[CH2:41][CH3:42])([CH3:43])[CH3:44].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[Cl:45][CH2:46][Cl:47]>>[CH3:7][n:8]1[c:9]([C:17](=[O:19])[NH:32][c:31]2[cH:30][cH:29][c:28]([B:23]3[O:22][C:21]([CH3:20])([CH3:35])[C:25]([CH3:26])([CH3:27])[O:24]3)[cH:34][cH:33]2)[cH:10][c:11]2[cH:12][cH:13][cH:14][cH:15][c:16]12

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 276951H-Indole-2-carboxylic acid, 1-methyl-HCID 65578Oxalyl chlorideHCID 81531DiisopropylethylamineHCID 27346204-(Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Product 1

HCID 184505431-methyl-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-indole-2-carboxamide

Sources & evidence

ORD record
ord-300bfa8ffcd8417f8e80404192ccecdc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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