Dimethyl Sulfate → 5-bromo-7-fluoro-1-methyl-1H-indazole

HRID 1995944

Reaction equation

HRID 1995944 reaction equation
[F:1][c:2]1[c:11]([c:7]2[cH:6][c:4]([Br:5])[cH:3]1)[nH:10][n:9][cH:8]2.[CH3:12]OS(OC)(=O)=O>>[CH3:12][n:10]1[c:11]([c:7]2[cH:8][n:9]1)[c:2]([F:1])[cH:3][c:4]([Br:5])[cH:6]2

Participants

6

Reactant 2

HCID 6497Dimethyl SulfateHCID 667931105-Bromo-7-fluoro-1H-indazole

Product 1

HCID 840568825-bromo-7-fluoro-1-methyl-1H-indazole

Reagents, catalysts & solvents 3

HCID 522689Potassium FluorideReagentHCID 8028TetrahydrofuranSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
25 °C

Sources & evidence

ORD record
ord-93120d7c3e3e45a9aa3406fe1a39f8e7
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Linked notes

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