Dichloromethane → Benzyl 4-Hydroxy-1-piperidinecarboxylate

Reaction equation

[CH3:8][CH2:9][N:10]([CH2:11][CH3:12])[CH2:13][CH3:14].[Cl:15][C:16](=[O:17])[O:18][CH2:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1.[Cl:26][CH2:27][Cl:28].[NH:1]1[CH2:2][CH2:3][CH:4]([OH:7])[CH2:5][CH2:6]1>>[N:1]1([C:16](=[O:17])[O:18][CH2:19][c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[CH2:2][CH2:3][CH:4]([OH:7])[CH2:5][CH2:6]1

Participants

Reactant 4

HCID 6344Dichloromethane

HCID 8471Triethylamine

HCID 10387Benzyl chloroformate

HCID 79341Piperidin-4-ol

Product 1

HCID 2794620Benzyl 4-Hydroxy-1-piperidinecarboxylate

Sources & evidence

ORD record: ord-d9755a65e5c8494f8cd21dd8914f569b
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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