Phenylboronic acid pinacol ester → 1-[(4-Methylphenyl)sulfonyl]-4-phenylpiperidine
Reaction equation
CC1(C(C)(C)OB(c2[cH:5][cH:4][cH:3][cH:2][cH:1]2)O1)C.[CH3:6][c:7]1[cH:12][cH:11][c:10]([S:13]([N:16]2[CH2:21][CH2:20][CH:19]([C:22](ON3C(=O)c(c4C3=O)c(Cl)c(Cl)c(Cl)c4Cl)=O)[CH2:18][CH2:17]2)(=[O:15])=[O:14])[cH:9][cH:8]1>>[CH3:6][c:7]1[cH:12][cH:11][c:10]([S:13]([N:16]2[CH2:21][CH2:20][CH:19]([c:22]3[cH:5][cH:4][cH:3][cH:2][cH:1]3)[CH2:18][CH2:17]2)(=[O:15])=[O:14])[cH:9][cH:8]1Participants
8
Reactant 2
Product 1
Reagents, catalysts & solvents 5
Conditions
- Temperature
- 60 °C
Sources & evidence
- ORD record
- ord-d0de288f2cc147338c3423813946439c
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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