Trifluoroacetic acid → 2-Cyclohexyl-4-methylquinoline

HRID 2034903

Reaction equation

HRID 2034903 reaction equation
OC(C(F)(F)F)=O.I[CH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:7][c:8]1[c:17]([c:12]2[n:11][cH:10][cH:9]1)[cH:16][cH:15][cH:14][cH:13]2>>[CH3:7][c:8]1[c:17]([c:12]2[n:11][c:10]([CH:1]3[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]3)[cH:9]1)[cH:16][cH:15][cH:14][cH:13]2

Participants

6

Reactant 3

HCID 6422Trifluoroacetic acidHCID 102854-MethylquinolineHCID 12289Iodocyclohexane

Product 1

HCID 4778742-Cyclohexyl-4-methylquinoline

Reagents, catalysts & solvents 2

HCID 6228DimethylformamideSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
25 °C

Sources & evidence

ORD record
ord-87decc41cf2c40ce8c8b9672cc51bbbb
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Linked notes

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