Trifluoroacetic acid → 2-Cyclohexyl-4-methylquinoline
Reaction equation
[CH3:1][c:2]1[c:11]([c:6]2[n:5][cH:4][cH:3]1)[cH:10][cH:9][cH:8][cH:7]2.I[CH:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1.OC(C(F)(F)F)=O>>[CH3:1][c:2]1[c:11]([c:6]2[n:5][c:4]([CH:12]3[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]3)[cH:3]1)[cH:10][cH:9][cH:8][cH:7]2Participants
6
Reactant 3
Product 1
Reagents, catalysts & solvents 2
Conditions
- Temperature
- 25 °C
Sources & evidence
- ORD record
- ord-0bf3247f71574e5cb4c359403fc6c84d
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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