Trifluoroacetic acid → 2-Cyclohexyl-4-methylquinoline

HRID 2034907

Reaction equation

HRID 2034907 reaction equation
[CH3:1][c:2]1[c:11]([c:6]2[n:5][cH:4][cH:3]1)[cH:10][cH:9][cH:8][cH:7]2.Br[CH:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1.OC(C(F)(F)F)=O>>[CH3:1][c:2]1[c:11]([c:6]2[n:5][c:4]([CH:12]3[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]3)[cH:3]1)[cH:10][cH:9][cH:8][cH:7]2

Participants

7

Reactant 3

HCID 6422Trifluoroacetic acidHCID 7960Cyclohexyl bromideHCID 102854-Methylquinoline

Product 1

HCID 4778742-Cyclohexyl-4-methylquinoline

Reagents, catalysts & solvents 3

HCID 178505916Tris[2-(2-pyridinyl)-3,5-difluorophenyl] iridium(III)CatalystHCID 176Acetic AcidSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
25 °C

Sources & evidence

ORD record
ord-ec3c95fa488f4c17adc5d45fe61bf8bc
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Linked notes

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