Triethylamine → Methyl 4-(cyclopentylethynyl)-2-methylbenzoate

HRID 204382

Reaction equation

HRID 204382 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH3:12])[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1.[C:13](#[CH:14])[CH:15]1[CH2:16][CH2:17][CH2:18][CH2:19]1.[CH3:20][CH2:21][N:22]([CH2:23][CH3:24])[CH2:25][CH3:26].[Cu:27]([I:28])[I:29].[Pd:30]([Cl:31])[Cl:32].[c:33]1([P:34]([c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[cH:47][cH:48][cH:49][cH:50][cH:51]1.[c:52]1([P:53]([c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[cH:66][cH:67][cH:68][cH:69][cH:70]1>>[c:2]1([C:14]#[C:13][CH:15]2[CH2:16][CH2:17][CH2:18][CH2:19]2)[cH:3][c:4]([CH3:12])[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1

Participants

7

Reactant 6

HCID 8471TriethylamineHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 83717Copper iodideHCID 136725CyclopentylacetyleneHCID 22031226Methyl 4-bromo-2-methylbenzoate

Product 1

HCID 57804197Methyl 4-(cyclopentylethynyl)-2-methylbenzoate

Sources & evidence

ORD record
ord-1694f1c4396144a8816b7f951b5bb21a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

Loading…