Dimethylformamide → 2-[(1-Benzyloxycarbonylamino-2-methylpropyl)-methoxy-phosphinoyloxy]-5-tert-butoxycarbonylamino-pentanoic acid methyl ester

HRID 2124275

Reaction equation

HRID 2124275 reaction equation
[CH3:34][O:35][P:36]([OH:37])(=[O:38])[CH:39]([CH:40]([CH3:41])[CH3:42])[NH:43][C:44](=[O:45])[O:46][CH2:47][c:48]1[cH:49][cH:50][cH:51][cH:52][cH:53]1.[CH3:54][O:55][C:56]([CH:57]([CH2:58][CH2:59][CH2:60][NH:61][C:62](=[O:63])[O:64][C:65]([CH3:66])([CH3:67])[CH3:68])[OH:69])=[O:70].[CH3:85][CH2:86][O:87][C:88](=[O:89])[CH3:90].[CH:71]([N:72]([CH2:73][CH3:74])[CH:75]([CH3:76])[CH3:77])([CH3:78])[CH3:79].[O:80]=[CH:81][N:82]([CH3:83])[CH3:84].[P-:1]([F:2])([F:3])([F:4])([F:5])([F:6])[F:7].[n:8]1([O:9][P+:10]([N:11]2[CH2:12][CH2:13][CH2:14][CH2:15]2)([N:16]2[CH2:17][CH2:18][CH2:19][CH2:20]2)[N:21]2[CH2:22][CH2:23][CH2:24][CH2:25]2)[c:26]2[cH:27][cH:28][cH:29][cH:30][c:31]2[n:32][n:33]1>>[CH3:34][O:35][P:36](=[O:37])([CH:39]([CH:40]([CH3:41])[CH3:42])[NH:43][C:44](=[O:45])[O:46][CH2:47][c:48]1[cH:49][cH:50][cH:51][cH:52][cH:53]1)[O:69][CH:57]([C:56]([O:55][CH3:54])=[O:70])[CH2:58][CH2:59][CH2:60][NH:61][C:62](=[O:63])[O:64][C:65]([CH3:66])([CH3:67])[CH3:68]

Participants

8

Reactant 7

HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 2724700Benzotriazol-1-yl-oxytripyrrolidinophosphoniumHCID 10380108(1-Benzyloxycarbonylamino-2-methyl-propyl)-phosphonic acid monomethyl esterHCID 543300255-Tert-butoxycarbonylamino-2-hydroxy-pentanoic acid methyl ester

Product 1

HCID 543920182-[(1-Benzyloxycarbonylamino-2-methylpropyl)-methoxy-phosphinoyloxy]-5-tert-butoxycarbonylamino-pentanoic acid methyl ester

Sources & evidence

ORD record
ord-069b9855ddc749b89d70578171a924fe
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Linked notes

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