4-Methylmorpholine → N-{4-[(3-Chloro-4-fluoro-phenyl)amino]-3-cyano-6-quinolinyl}-2-butynamide
Reaction equation
[C:1]([C:2]#[C:3][CH3:4])(=[O:5])[OH:6].[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[CH3:15][N:16]1[CH2:17][CH2:18][O:19][CH2:20][CH2:21]1.[Cl:7][C:8]([O:9][CH2:10][CH:11]([CH3:12])[CH3:13])=[O:14].[NH2:22][c:23]1[cH:24][c:25]2[c:26]([NH:35][c:36]3[cH:37][c:38]([Cl:43])[c:39]([F:42])[cH:40][cH:41]3)[c:27]([C:33]#[N:34])[cH:28][n:29][c:30]2[cH:31][cH:32]1>>[C:1]([C:2]#[C:3][CH3:4])(=[O:6])[NH:22][c:23]1[cH:24][c:25]2[c:26]([NH:35][c:36]3[cH:37][c:38]([Cl:43])[c:39]([F:42])[cH:40][cH:41]3)[c:27]([C:33]#[N:34])[cH:28][n:29][c:30]2[cH:31][cH:32]1Participants
6
