Dimethylformamide → Methyl 2-[5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(diethylamino)-3-methyl-2-oxopiperidin-3-yl]acetate

HRID 2157917

Reaction equation

HRID 2157917 reaction equation
[CH2:1]([CH3:2])[I:3].[CH:32]([CH3:33])([N:34]([CH2:35][CH3:36])[CH:37]([CH3:38])[CH3:39])[CH3:40].[NH2:4][N:5]1[C:6](=[O:31])[C:7]([CH3:25])([CH2:26][C:27](=[O:28])[O:29][CH3:30])[CH2:8][CH:9]([c:18]2[cH:19][c:20]([Cl:24])[cH:21][cH:22][cH:23]2)[CH:10]1[c:11]1[cH:12][cH:13][c:14]([Cl:17])[cH:15][cH:16]1.[O:41]=[CH:42][N:43]([CH3:44])[CH3:45]>>[CH2:1]([CH3:2])[N:4]([N:5]1[C:6](=[O:31])[C:7]([CH3:25])([CH2:26][C:27](=[O:28])[O:29][CH3:30])[CH2:8][CH:9]([c:18]2[cH:19][c:20]([Cl:24])[cH:21][cH:22][cH:23]2)[CH:10]1[c:11]1[cH:12][cH:13][c:14]([Cl:17])[cH:15][cH:16]1)[CH2:32][CH3:33]

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 6340IodoethaneHCID 81531DiisopropylethylamineHCID 76834778Methyl 2-[1-amino-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-2-oxopiperidin-3-yl]acetate

Product 1

HCID 76834833Methyl 2-[5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(diethylamino)-3-methyl-2-oxopiperidin-3-yl]acetate

Sources & evidence

ORD record
ord-c3b4344e0e2448c5a93f0d7d2174d3c1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Linked notes

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