2-Amino-5-methylpyridine → HCID 178423118, compound

HRID 223883

Reaction equation

HRID 223883 reaction equation
CC1=CC=C(N)N=C1.[C-]#[N+]C1CCCCC1.[H]C(=O)C1=C(F)C=C(C=C1)C(F)(F)F>>CC1=CN2C(C=C1)=NC(=C2NC1CCCCC1)C1=C(F)C=C(C=C1)C(F)(F)F

Participants

6

Reactant 3

HCID 153482-Amino-5-methylpyridineHCID 79129Cyclohexyl isocyanideHCID 5229292-Fluoro-4-(trifluoromethyl)benzaldehyde

Product 1

HCID 178423118HCID 178423118, compoundYield 23.383%

Reagents, catalysts & solvents 2

HCID 6422Trifluoroacetic acidCatalystHCID 3776IsopropanolSolvent2×

Conditions

Temperature
22 °C

Sources & evidence

ORD record
ord-270801e1798747fb9e64df2e0f257301
Source dataset
Imidazopyridines dataset

Linked notes

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