2-Phenylpropanal → N-cyclohexyl-6-methyl-2-(1-phenylethyl)imidazo[1,2-a]pyridin-3-amine

HRID 223925Notes

Reaction equation

HRID 223925 reaction equation
CC1=CC=C(N)N=C1.[C-]#[N+]C1CCCCC1.CC(C=O)C1=CC=CC=C1>>CC(C1=C(NC2CCCCC2)N2C=C(C)C=CC2=N1)C1=CC=CC=C1

Participants

6

Reactant 3

HCID 71462-PhenylpropanalHCID 153482-Amino-5-methylpyridineHCID 79129Cyclohexyl isocyanide

Product 1

HCID 5091806N-cyclohexyl-6-methyl-2-(1-phenylethyl)imidazo[1,2-a]pyridin-3-amineYield 25.486%

Reagents, catalysts & solvents 2

HCID 6422Trifluoroacetic acidCatalystHCID 3776IsopropanolSolvent2×

Conditions

Temperature
22 °C

Sources & evidence

ORD record
ord-4feec23fd20946f5b035f95514b7078b
Source dataset
Imidazopyridines dataset

Reaction notes

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