Oxalyl chloride → 2,3-Dichloro-6-iodobenzoic acid chloride

HRID 2287343

Reaction equation

HRID 2287343 reaction equation
[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[C:7]([I:12])[C:3]=1[C:4](O)=[O:5].C(Cl)(=O)C([Cl:16])=O>CN(C=O)C.C(OCC)(=O)C>[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[C:7]([I:12])[C:3]=1[C:4]([Cl:16])=[O:5]

Participants

5

Reactant 2

HCID 65578Oxalyl chlorideHCID 220088162,3-Dichloro-6-iodobenzoic acid

Product 1

HCID 542920312,3-Dichloro-6-iodobenzoic acid chloride

Reagents, catalysts & solvents 2

HCID 6228DimethylformamideCatalystHCID 8857Ethyl AcetateSolvent

Procedure

DMF (one drop) was added to a stirred solution of 2,3-dichloro-6-iodobenzoic acid (1.53 g, 4.83 mmol) and oxalyl chloride (2 ml) in ethyl acetate (20 ml). After 2 hours, the solution was evaporated and the product was used immediately.

Workup

  1. customthe solution was evaporated

Sources & evidence

ORD record
ord-fcb6181488fb4a4085cac970464cc3d3
Source dataset
uspto-grants-2000_07
Patent number
US06083952

Linked notes

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