Tetrahydrofuran → 2-fluoro-N-(thiazolo[4,5-c]pyridin-2-yl)-5-(trifluoromethyl)benzamide

HRID 2323979

Reaction equation

HRID 2323979 reaction equation
[CH2:32]([P:33]([OH:34])(=[O:35])[OH:36])[CH2:37][CH3:38].[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[CH3:44][CH2:45][O:46][C:47]([CH3:48])=[O:49].[F:11][c:12]1[c:13]([C:14](=[O:15])[OH:16])[cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]1.[s:1]1[c:2]([NH2:10])[n:3][c:4]2[cH:5][n:6][cH:7][cH:8][c:9]12>>[s:1]1[c:2]([NH:10][C:14]([c:13]2[c:12]([F:11])[cH:20][cH:19][c:18]([C:21]([F:22])([F:23])[F:24])[cH:17]2)=[O:15])[n:3][c:4]2[cH:5][n:6][cH:7][cH:8][c:9]12

Participants

7

Reactant 6

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 204484Propylphosphonic acidHCID 6882922-Fluoro-5-(trifluoromethyl)benzoic acidHCID 14252938(1,3)Thiazolo(4,5-c)pyridin-2-amine

Product 1

HCID 866445402-fluoro-N-(thiazolo[4,5-c]pyridin-2-yl)-5-(trifluoromethyl)benzamide

Sources & evidence

ORD record
ord-9ccdb1802563441ba94d77d09de89ab7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Linked notes

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