Sodium ion → N-[(7-phenyl-9,9a-dihydro-3-oxo-1H,3H-oxazolo[3,4-a]indol-1-yl)methyl]acetamide

HRID 2332183

Reaction equation

HRID 2332183 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[N:7]1[CH:6]([CH2:5]2)[CH:13]([CH2:14][NH:15][C:16]([CH3:17])=[O:18])[O:12][C:11]1=[O:19].[CH2:40]([Cl:41])[Cl:42].[Na+:29].[Na+:30].[O-:31][C:32](=[O:33])[O-:34].[O:35]1[CH2:36][CH2:37][CH2:38][CH2:39]1.[OH:20][B:21]([OH:22])[c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1.[Pd:119].[c:100]1([P:101]([c:102]2[cH:103][cH:104][cH:105][cH:106][cH:107]2)[c:108]2[cH:109][cH:110][cH:111][cH:112][cH:113]2)[cH:114][cH:115][cH:116][cH:117][cH:118]1.[c:43]1([P:44]([c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)[c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[cH:57][cH:58][cH:59][cH:60][cH:61]1.[c:62]1([P:63]([c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)[c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)[cH:76][cH:77][cH:78][cH:79][cH:80]1.[c:81]1([P:82]([c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)[c:89]2[cH:90][cH:91][cH:92][cH:93][cH:94]2)[cH:95][cH:96][cH:97][cH:98][cH:99]1>>[c:2]1(-[c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[N:7]1[CH:6]([CH2:5]2)[CH:13]([CH2:14][NH:15][C:16]([CH3:17])=[O:18])[O:12][C:11]1=[O:19]

Participants

9

Reactant 8

HCID 923Sodium ion2×HCID 6344DichloromethaneHCID 8028TetrahydrofuranHCID 11776Triphenylphosphine4×HCID 19660Carbonate IonHCID 23938PalladiumHCID 66827Phenylboronic AcidHCID 19795216N-[(7-bromo-9,9a-dihydro-3-oxo-1H,3H-oxazolo[3,4-a]indol-1-yl)methyl]acetamide

Product 1

HCID 54251491N-[(7-phenyl-9,9a-dihydro-3-oxo-1H,3H-oxazolo[3,4-a]indol-1-yl)methyl]acetamide

Sources & evidence

ORD record
ord-3b2bef184c554e6f9a39348a9e41de98
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Linked notes

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