Ammonia → 3-Chloro-5-hydroxybenzamide

Reaction equation

[CH3:31][OH:32].[CH:19]([N:22]([CH2:20][CH3:21])[CH:23]([CH3:24])[CH3:25])([CH3:26])[CH3:27].[Cl:12][C:13]([C:14]([Cl:15])=[O:16])=[O:17].[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[OH:7])[cH:8][c:9]([OH:11])[cH:10]1.[Cl:28][CH2:29][Cl:30].[NH3:18].[O:33]=[CH:34][N:35]([CH3:36])[CH3:37]>>[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH2:22])[cH:8][c:9]([OH:11])[cH:10]1

Participants

Reactant 7

HCID 222Ammonia

HCID 887Methanol

HCID 6228Dimethylformamide

HCID 6344Dichloromethane

HCID 65578Oxalyl chloride

HCID 81531Diisopropylethylamine

HCID 130716463-Chloro-5-hydroxybenzoic Acid

Product 1

HCID 150273143-Chloro-5-hydroxybenzamide

Sources & evidence

ORD record: ord-7efd9aeb854a46fe87934f58b5ae8e53
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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