Hydrochloric Acid → 2-Ethoxycarbonylacetylamino-4-(4-methoxyphenyl)-5-(3-pyridyl)-1,3-thiazole

HRID 2346791

Reaction equation

[CH2:21]([CH3:22])[O:23][C:24](=[O:25])[CH2:26][C:27](=[O:28])[Cl:29].[CH3:32][N:33]([CH3:34])[CH:35]=[O:36].[ClH:30].[NH2:1][c:2]1[s:3][c:4](-[c:15]2[cH:16][n:17][cH:18][cH:19][cH:20]2)[c:5](-[c:7]2[cH:8][cH:9][c:10]([O:13][CH3:14])[cH:11][cH:12]2)[n:6]1.[Na:31]>>[NH:1]([c:2]1[s:3][c:4](-[c:15]2[cH:16][n:17][cH:18][cH:19][cH:20]2)[c:5](-[c:7]2[cH:8][cH:9][c:10]([O:13][CH3:14])[cH:11][cH:12]2)[n:6]1)[C:27]([CH2:26][C:24]([O:23][CH2:21][CH3:22])=[O:25])=[O:28]

Participants

Reactant 5

HCID 313Hydrochloric Acid

HCID 6228Dimethylformamide

HCID 118931Ethyl 3-chloro-3-oxopropionate

HCID 30248942-Thiazolamine, 4-(4-methoxyphenyl)-5-(3-pyridinyl)-

HCID 5360545Sodium

Product 1

HCID 98009472-Ethoxycarbonylacetylamino-4-(4-methoxyphenyl)-5-(3-pyridyl)-1,3-thiazole

Sources & evidence

ORD record: ord-a959a9beeb514aef93a3a92e32d11f0b
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Linked notes

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