Tetrahydrofuran → N-Acetyl-7-(piperidin-1-ylsulfonyl)-1,2,3,4-tetrahydroisoquinoline

HRID 2348029

Reaction equation

[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][c:6]2[cH:7][c:8]([S:14](=[O:15])(=[O:16])[Cl:17])[cH:9][cH:10][c:11]2[CH2:12][CH2:13]1.[CH2:18]1[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]1.[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH:24]([N:25]([CH:26]([CH3:27])[CH3:28])[CH2:29][CH3:30])([CH3:31])[CH3:32]>>[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][c:6]2[cH:7][c:8]([S:14](=[O:15])(=[O:16])[N:21]3[CH2:20][CH2:19][CH2:18][CH2:23][CH2:22]3)[cH:9][cH:10][c:11]2[CH2:12][CH2:13]1

Participants

Reactant 4

HCID 8028Tetrahydrofuran

HCID 8082Piperidine

HCID 81531Diisopropylethylamine

HCID 126069042-Acetyl-1,2,3,4-tetrahydroisoquinoline-7-sulfonyl chloride

Product 1

HCID 18176579N-Acetyl-7-(piperidin-1-ylsulfonyl)-1,2,3,4-tetrahydroisoquinoline

Sources & evidence

ORD record: ord-6cf9e9d22d2b4e34a1ba4989db9a264a
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Linked notes

Loading…